KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
9.09
Human Site:
S1240
Identified Species:
15.38
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
S1240
Q
E
G
A
M
L
L
S
P
E
P
P
A
K
E
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
P1095
T
P
A
P
V
E
V
P
V
P
E
R
V
A
G
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
V29
N
K
E
L
E
L
S
V
P
K
F
K
V
G
P
Dog
Lupus familis
XP_543382
1925
209302
S1244
E
E
G
A
K
L
L
S
P
E
P
P
A
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S1301
T
Q
G
D
M
L
L
S
P
E
L
P
A
R
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
V100
F
K
I
D
E
F
Y
V
G
P
V
P
P
K
Q
Chicken
Gallus gallus
Q5F3P8
2008
223067
T1309
C
L
E
T
H
V
K
T
K
L
P
S
A
V
E
Frog
Xenopus laevis
Q66J90
1938
216239
N1222
P
V
P
L
V
P
D
N
A
P
P
A
V
Q
E
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
E1152
D
E
L
D
V
D
L
E
V
K
I
P
V
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
N1045
T
I
L
R
K
I
P
N
T
P
K
L
N
E
E
Honey Bee
Apis mellifera
XP_395451
1406
159180
I811
P
T
G
R
E
T
P
I
P
N
I
K
I
K
D
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
D912
T
S
A
R
V
S
E
D
E
S
D
S
D
S
T
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
K1190
Q
E
M
K
I
I
M
K
K
D
L
N
R
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
F718
V
N
A
R
K
H
G
F
N
D
P
F
A
R
A
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
0
13.3
80
N.A.
66.6
N.A.
N.A.
13.3
20
13.3
20
N.A.
6.6
20
0
20
P-Site Similarity:
100
13.3
26.6
86.6
N.A.
80
N.A.
N.A.
26.6
33.3
33.3
40
N.A.
26.6
26.6
6.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
22
15
0
0
0
0
8
0
0
8
36
8
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
22
0
8
8
8
0
15
8
0
8
0
8
% D
% Glu:
8
29
15
0
22
8
8
8
8
22
8
0
0
8
43
% E
% Phe:
8
0
0
0
0
8
0
8
0
0
8
8
0
0
0
% F
% Gly:
0
0
29
0
0
0
8
0
8
0
0
0
0
15
8
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
8
15
0
8
0
0
15
0
8
0
0
% I
% Lys:
0
15
0
8
22
0
8
8
15
15
8
15
0
29
8
% K
% Leu:
0
8
15
15
0
29
29
0
0
8
15
8
0
0
0
% L
% Met:
0
0
8
0
15
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
8
8
0
0
0
0
0
15
8
8
0
8
8
0
0
% N
% Pro:
15
8
8
8
0
8
15
8
36
29
36
36
8
8
8
% P
% Gln:
15
8
0
0
0
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
0
0
0
29
0
0
0
0
0
0
0
8
8
15
0
% R
% Ser:
0
8
0
0
0
8
8
22
0
8
0
15
0
8
0
% S
% Thr:
29
8
0
8
0
8
0
8
8
0
0
0
0
0
8
% T
% Val:
8
8
0
0
29
8
8
15
15
0
8
0
29
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _